McPAT is an architectural modeling tool for chip multiprocessors (CMP). The main focus of McPAT is accurate power and area modeling, and a target clock rate is used as a design constraint. McPAT performs automatic extensive search to find optimal designs that satisfy the target clock frequency.

FireSim is an open-source FPGA-accelerated full-system hardware simulation platform that makes it easy to validate, profile, and debug RTL hardware implementations at 10s to 100s of MHz.

GPGPU-Sim is a cycle-level simulator modeling contemporary graphics processing units (GPUs) running GPU computing workloads written in CUDA or OpenCL.

SimCXL is a full-system, cycle-level simulator based on gem5 that provides complete support for all three CXL sub-protocols and all three types of CXL devices.

The gem5 simulator is a modular platform for computer-system architecture research, encompassing system-level architecture as well as processor microarchitecture. It is primarily used to evaluate new hardware designs, system software changes, and compile-time and run-time system optimizations.

The Weather Research and Forecasting (WRF) Model is a next-generation mesoscale numerical weather prediction system designed for both atmospheric research and operational forecasting applications.

FEniCSx is a popular open-source (LGPLv3) computing platform for solving partial differential equations (PDEs).

OpenFOAM is the free, open source CFD software developed primarily by OpenCFD Ltd.

NWChem aims to provide its users with computational chemistry tools that are scalable both in their ability to treat large scientific computational chemistry problems efficiently, and in their use of available parallel computing resources from high-performance parallel supercomputers to conventional workstation clusters.

CP2K is a quantum chemistry and solid state physics software package that can perform atomistic simulations of solid state, liquid, molecular, periodic, material, crystal, and biological systems.